Breast cancer: Scientists find five times more genes linked to disease than previously known

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Scientists have found that DNA errors linked to an increased risk of breast cancer affect five times as many genes than were previously known

The study found 352 DNA "errors" linked to an increased risk of developing breast cancer. File pic

Previous research has found 150 areas in the genome that contain genetic changes that affect breast cancer risk, but experts have rarely been able to pinpoint the specific variants and genes involved.But, added together, they give women a clearer picture of their genetic risk and the best strategies to prevent its onset, the researchers said.

Dr Alison Dunning, from the University of Cambridge, said:"This incredible haul of newly-discovered breast cancer genes provides us with many more genes to work on, most of which have not been studied before. "It will help us build up a much more detailed picture of how breast cancer arises and develops. But the sheer number of genes now known to play a role emphasises how complex the disease is."It comes after a separate study - by a team from University College London - found a group of cells that play a role in the body's immune response could hold the key to"more effective" cancer treatments.

Scientists found that"T cells" - a subset of white blood cells - are activated to kill cancer cells after an experimental study of immunotherapy in mice.

 

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