that causes hair to thin. The team is hopeful that their discovery could lead to a cure for baldness in the near future.
For example, follicle cells become stressed as they age, slowing down growth. An overactivated IRS, however, can cause cell death, stopping rather than slowing hair growth.Dr.Talveen Purba, senior author of the study, said, “We’re incredibly hopeful as we believe the activation of this pathway could play an important biological role in restricting hair growth in people with hair loss conditions, meaning that targeting it could lead to new treatments.
Derek Pye, chief technician of the research group and co-author of the study, reported, “When we look at hair follicles under the microscope, it’s striking how consistent the response is between hair follicles from different people.”According to Purba, while no drugs known to influence ISR are currently available, there are some under investigation in other contexts.By the time they reach middle age, roughly 85% of men are affected by hair loss.
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