Study reveals diverse risk factors for healthy aging in Latin America

Trinity College DublinJun 17 2024 A pioneering study published today in the journal Nature Aging has unveiled significant heterogeneity in the risk factors affecting healthy aging in Latin America and emphasized the limitations of current models of brain health, which are primarily based on data from high-income countries. The research was conducted by researchers from Trinity College Dublin , and by colleagues in Universidad Adolfo Ibanez and Pontificia Universidad Javeriana among others.

The study involved a comprehensive meta-analysis of multiple studies, ultimately including over 146,000 participants. Results highlighted significant but heterogeneous effects on cognition and functional ability, with varied impacts from demographics, mental health, health status, and social determinants.

Agustin Ibanez, first author of the study, Atlantic Fellow at the Global Brain Health Institute, Trinity College Dublin and Director of BrainLat UAI Related Stories"Developing predictive models tailored to the region's unique demographic, genetic, and socioeconomic contexts is essential. Bridging this gap requires advanced computational approaches that integrate theories of brain function and its interaction with the exposome."

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