FDA official: The risk of secondary cancer from CAR-T therapy, pioneered at Penn, is less than feared

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Peter Mark, head of the FDA Center for Biologics Evaluation and Research, spoke Friday at an event held by the Sino-American Pharmaceutical Professionals Association - Greater Philadelphia.

FDA official: The risk of secondary cancer from CAR-T therapy, pioneered at Penn, is less than feared

Most look to be secondary cancers affecting the T cells of patients who already have related cancers, he said. In a few cases, however, there are signs that patients developed secondary cancer in the type of white blood cells that were genetically modified as part of their treatment, Marks said. The risk is probably on the order of 1 in 10,000 people treated, he said.

 

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