The role of banana lectin in mitigating inflammatory bowel disease

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Banana News

Inflammatory Bowel Disease,Anti-Inflammatory,Colon

The therapeutic role of recombinant banana lectin (rBanLec) concerning IBD control and raising vaccination rates.

By Dr. Priyom Bose, Ph.D.Jun 3 2024Reviewed by Lily Ramsey, LLM Inflammatory bowel disease patients are less likely to be vaccinated compared to that of the general population. Putting them at a greater risk of contracting vaccine-preventable illnesses.

IBD patients are less often vaccinated and could experience more health complications compared to the general population. The risk of infections is elevated, given IBD treatment potentially suppresses the immune system. Related StoriesThe model of colitis that was used was induced by 2,4,6-trinitrobenzene sulfonic acid . As a continuous treatment strategy, rBanLec’s isoform effectiveness was assessed.

Important beneficial effects of rBanLec were noted despite its inability to prevent experimental colitis. An inverse dose-dependent relationship was observed where the efficacy of rBanLec was higher at lower doses. The observed beneficial changes could be due to anti-inflammatory, immune responses generated following colitis onset or the lower cellular infiltration in the colon.

 

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