Drugs designed to treat diabetes and repurposed as miracle diet aids have taken over TikTok - and Hollywood. The weight loss caused by these weekly injectables is rapid and previously unattainable, people boast, showing off newly svelte bodies. But what are these drugs, how do they work - and what were they originally designed to do? Mounjaro, Ozempic, Wegovy - what are they? Let's start with the most well-known of the trio: Ozempic.
In terms of weight loss, in clinical trials people lost up to 20% of their body weight on tirzepatide and 15% on semaglutide. They sound like miracle drugs for people wanting to lose weight - what's the catch? There are a few downsides. First off, the listed side effects: nausea, vomiting and diarrhoea, bad enough for about 5% of people in the semaglutide trial to stop taking it and 6-7% in the tirzepatide trial. People in the semaglutide trial also experienced problems with gallstones.
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