Meet the Utah professor who believes she's on the cusp of an Alzheimer's breakthrough

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Health,Alzheimer's Disease,Cancer

Dr Donna J Cross [left] at the University of Utah discovered that a cancer drug reversed signs of Alzheimer's in lab mice, a discovery that could translate to a game-changing treatment.

READ MORE: Alzheimer'sFirst, Dr Donna J Cross saw Alzheimer’s rob her grandmother of her independence, personality, and ultimately her life.

She believes she's on the cusp of a breakthrough after a repurposed cancer drug caused the 'complete reversal' of cognitive decline in mice with Alzheimer's.Alzheimer's disease is the most common cause of dementia and an estimated 6 million Americans have it The finding was a major win for Dr Cross and fellow researchers, especially given the lengthy trail of failed drugs that targeted a long-accepted hallmark of Alzheimer's.

‘We would treat not just Alzheimer’s, but also any kind of dementia: ALS, Parkinson’s, multiple sclerosis, spinal cord injury, any kind of condition where nerve cells are dying.’Advertisement She would need to create a version of the drug that could cross the human blood-brain barrier , which is no easy feat.

But Dr Cross discovered that administering the drug up the nose was effective at crossing the BBB in mice, and would presumably do the same in humans.

 

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