DoD grant awarded for investigating alternative polyadenylation in prostate cancer

📆 5/11/2024 2:16 AM
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Cancer News

Prostate,Prostate Cancer,RNA

A team led by Dr. Eddie Imada, assistant professor of research in pathology and laboratory medicine, has been awarded a three-year, $1.5 million United States Department of Defense grant for research on a cellular process called alternative polyadenylation and its role in prostate cancer.

May 10 2024Weill Cornell Medicine

At first glance, polyadenylation isn't an obvious culprit in cancer. It is an evolutionarily ancient and routine process that adds a tail of RNA nucleotide "letters"—all of them adenosines, represented by the letter "A" in the genetic code—to one end of a gene's newly made RNA transcript. This polyA tail and other routine modifications turn the transcript into a messenger RNA .

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