By Pooja Toshniwal PahariaMay 7 2024Reviewed by Lily Ramsey, LLM In a recent study published in JAMA Network Open, researchers compared the risk of cancer in children born by medically assisted reproduction to infants conceived naturally.
About the study In the present study, researchers investigated whether cancer risk differed between infants born through medically assisted reproduction and those conceived naturally. The researchers compared cancer risk, overall and stratified by cancer subtype, between children born following MAR and those conceived spontaneously by performing Cox proportional regression modeling to derive the hazard ratios , adjusted for mother and child factors at birth.
Case patients were children with cancer meeting one or more of the following criteria: had at least two hospitalizations with cancer diagnosis, at least one hospitalization with cancer diagnosis and one hospitalization for oncologic treatment or a diagnosis of childhood cancer, or one hospitalization with cancer diagnosis followed by death within six months.
In total, 3.1% of offspring were born after medically assisted reproduction, including 1.6% following fresh ET, 0.8% following FET, and 0.7% after AI.
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