Study suggests a common brain network exists between heart rate deceleration and depression

Apr 26 2024Brigham and Women's Hospital A new study by researchers at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, suggests a common brain network exists between heart rate deceleration and depression.

Siddiqi said the idea first developed during a conference in Croatia where researchers from the Netherlands were presenting heart-brain coupling data. "They showed that not only can TMS transiently lower the heart rate, but it matters where you stimulate," Siddiqi said, adding that most exciting part of the study for him is the potential to give the rest of the world easier access to this precision targeted treatment for depression.

"We wanted to see if there would be mostly heart-brain coupling in the connected areas," Dijkstra said. "For 12 out of 14 usable data sets, we found we would have a very high accuracy of defining an area that is connected by just measuring heart rate during brain stimulation."

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