Brain region associated with movement found to be abnormal in children with developmental language disorder

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A rigorous analysis of numerous studies concludes that a part of the brain traditionally associated with movement is abnormal in children with developmental language impairments, according to Georgetown University Medical Center neuroscientists.

Mar 15 2024Georgetown University Medical Center The discovery has the potential to improve both the diagnosis and treatment of the language difficulties.

To better understand why the language impairments occur, the researchers analyzed the results of 22 articles examining brain structures in people with the disorder, and then employed a new computational method to identify common patterns of abnormalities across the studies. They determined that the anterior neostriatum was abnormal in 100% of the studies that examined the structure, with fewer abnormalities in all other parts of the brain.

Michael T. Ullman, PhD, study's lead author, professor of neuroscience and director of the Brain and Language Laboratory at Georgetown University Medical Center "Continuing research efforts to further understand the neurobiology of developmental language disorder, especially the role of the basal ganglia, could help the many children who are affected by these problems," concludes Ullman.

 

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