How high blood sugar, hypertension and obesity can add up to cancer risk

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It's known that obesity is linked to many cancers. A study shows metabolic syndrome, which includes factors like high blood pressure and insulin resistance, also drives increased risk.

It's known that obesity is linked to many cancers. A study shows metabolic syndrome, which includes factors like high blood pressure and insulin resistance, also drives increased risk.People with metabolic syndrome, which can include high blood pressure, high cholesterol, high blood sugar and several other conditions, are at higher risk of getting cancer, a new study finds.

"It's very compelling," says Denis, who wasn't involved in the study."They're seeing that as you cluster these factors, risk goes up which makes perfect sense to me.", which is used to measure chronic inflammation. Metabolic syndrome and higher levels of this protein were"significantly associated with subsequent breast, endometrial, colorectal and liver cancers," the authors conclude.

The large number of people enrolled, the prospective design and its"robust assessment of metabolic parameters" are all strengths of the new study, saysThe study used a definition of metabolic syndrome that required a person to have a large waistline – what the researchers called"central obesity" – plus two other conditions.

In future research, Winn says the hope is to more precisely identify which conditions raise someone's risk, and by how much, when they have a constellation of metabolic problems.

 

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