Mediterranean diet and exercise reshape gut microbiome, aiding weight loss

By Hugo Francisco de SouzaMar 4 2024Reviewed by Benedette Cuffari, M.Sc. In a recent study published in The American Journal of Clinical Nutrition, researchers investigate the health benefits of the Mediterranean diet and physical activity interventions on overweight and obese participants by measuring changes in fecal metabolomic- and gut microbiota.

The high concentrations of dietary fiber and anti-inflammatory nutraceuticals in the MedDiet have also been associated with promoting and persisting beneficial gut microbiota. To date, the metabolomic consequences of these associations remain unknown. Data collection included dietary and lifestyle information obtained through the er-MedDiet questionnaire, a 17-item derivation of the 14-item Mediterranean Diet Adherence Screener questionnaire. Blood and stool samples were also collected during baseline assessments and routine follow-up. Anthropometric measurements and demographic data were further obtained from medical and government records.

Study findings The present study highlights the combined health benefits of a dietitian-guided MedDiet alongside physical activity compared to an ad libitum MedDiet.

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