Colorectal cancer is the third most common form of cancer worldwide, with around 1.9 million newly diagnosed cases and 900,000 deaths every year. Therefore, preventive substances represent an urgent clinical need. Aspirin/acetylsalicylic acid has proven to be one of the most promising candidates for the prevention of colorectal cancer.
Overall, the results show that the miR-34 genes are necessary for mediating the inhibiting effect of aspirin on colorectal cancer cells. Aspirin was thus unable to prevent migration, invasion, and metastasis in miR-34-deficient cancer cells. It was already known that the miR-34 genes are induced by the transcription factor p53 and mediate its effects.
A new study has found that there is no protection against colorectal cancer if people begin taking aspirin regularly after age 70. However, there appears to be such protection if aspirin is started ... The benefits of a daily aspirin may extend beyond heart health to colorectal cancer treatment, say City of Hope researchers who have found aspirin appears to reduce tumor growth and inhibit ...
Scientists have now discovered that a certain group of cancer drugs activates the cancer-promoting Wnt signalling pathway in colorectal cancer cells. This can lead to the ...Mummified Feces Reveals Pre-Columbian Cultures of the Caribbean Consumed a Diversity of Plants
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