Immune system: Mechanisms of alarmin release discovered

Many common illnesses such as arteriosclerosis and diabetes or neurodegenerative diseases such as Alzheimer's are associated with inflammatory processes. Gaining a better understanding of these processes is therefore an important stepping stone toward the development of new therapeutic approaches. Specific immune cells known as neutrophils play a decisive role in the initiation and maintenance of inflammatory processes in blood and tissue.

The research thus expands our knowledge of how the NLRP3 inflammasome works and opens up the possibility of therapeutically influencing inflammatory processes at a very early stage through modulation of the mechanisms involved in alarmin release.

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