Cervical Cancer Treatment Hailed as Most ‘Remarkable’ Breakthrough in 20 Years, Say Scientists

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A study found that new induction chemotherapy treatment accompanied by standard chemoradiation was effective in prolonging lives of cervical cancer patients.

David Chiu is a digital news writer for PEOPLE. A former PEOPLE intern from 2007 to 2008, he has been writing about news and entertainment for over 10 years.New trial findings showed that using existing, less expensive drugs prior to standard chemoradiation treatment may reduce the risk of death of women from cervical cancer by 35%.

For the study, 500 patients with cervical cancer — ranging from five countries and between the ages 24 to 78 — were recruited. Half of them received the new treatment that consisted of a six-week course of carboplatin and paclitaxel chemotherapy accompanied by the "usual" treatment of radiotherapy including chemoradiation, per BBC News. The other half, the control group, received just the standard treatment.

Based on the study's results, after five years, 80% of the women employing the new induction chemotherapy treatment were alive and 73% had not seen their cancer return or spread,reported. In contrast, of those who received just the standard radiotherapy treatment, 72% were alive and 64% did not see their cancer return or spread. “Induction chemotherapy followed by CRT significantly improves PFS and OS in LACC and should be considered a new standard of care,” the study concluded.

“Our trial shows that this short course of additional chemotherapy delivered immediately before the standard CRT can reduce the risk of the cancer returning or death by 35%,” said Dr. Mary McCormack, the lead researcher of the trial from UCL Cancer Institute and UCLH, per“Timing is everything when you’re treating cancer,” said Dr. Iain Foulkes, executive director of research and innovation at Cancer Research U.K., per.

“We’re excited for the improvements this trial could bring to cervical cancer treatment and hope short courses of induction chemotherapy will be rapidly adopted in the clinic,” Foulkes continued. says, there are approximately 11,500 new cases of cervical cancer diagnosed annually in the U.S. and 4,000 die as a result.

 

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