Spinal fluid test may enable earlier diagnosis of Parkinson's disease

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People with Parkinson’s disease have been found to have high levels of an enzyme called DOPA decarboxylase in the fluid around their brain and spinal cord

A sample of brain tissue from a person with Parkinson’s disease, showing clumps of protein known as Lewy bodies High levels of a certain enzyme in the fluid around a person’s brain and spinal cord could be a sign that they have Parkinson’s disease – potentially enabling the condition to be diagnosed earlier.

Hansson and his colleagues carried out tests on 81 people with Parkinson’s disease or DLB and 347 people who had no symptoms of the conditions. They collected each person’s cerebrospinal fluid, which bathes the brain and spinal cord, by inserting a needle into the spinal canal.

 

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