Transparent mouse could improve cancer drug tests

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Scientists say a new scanning method that can identify tiny tumours could revolutionise medical research.

Everything inside the mouse – its nerves, tissues and organs – are made invisible by a chemical processA new scanning method involving a see-through mouse could improve how cancer drugs are tested, by picking up tumours previously too small to detect.

The researchers say the method reveals far greater detail than existing scanning techniques. In one of the first applications the team has detected cancerous tumours in the first stages of formation. Normally lab mice are given cancer and scanned with conventional scans to see how the tumour has progressed. They are then treated with the cancer drug being tested and then scanned again to see what if any difference the treatment has had.

Mouse studies are often the starting point for learning about processes in the human body. But the new technique can be used on any animals. It could also be used to make human tissues and organs transparent, though it is unlikely to be used to make an entire human body transparent in the near future because there would be no medical advances that could be made from it at this stage.

 

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