Do Statins Reduce Risk for Diabetic Kidney Disease?

Finally, the researchers found a significant positive association between statin initiation and increased use of oral glucose-lowering drugs .

Although current Chinese guidelines recommend statin therapy for all patients with type 2 diabetes aged 40 years or older, 36.6% of eligible participants were prescribed statins during the study period,"which is lower than [the rates] in Canada and the United States ," write the authors."The suboptimal accordance with this recommendation might contribute to the higher risk of kidney disease progression we observed in our study population.

"Randomized controlled trials are considered the gold standard for evaluating efficacy of medications," said Mansi. He and his colleagues published athat also found a higher rate of renal disease progression in statin users compared with nonusers . "Statins should be prescribed to lower cardiovascular disease...not for preventing kidney disease," said Mansi. He suggested that the results of the current study may be related to the size of the study or the different confounders."For example, statin users may be more health-aware subjects, and hence, may have better outcomes because of their health awareness, not necessarily because of statins.

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