By Pooja Toshniwal PahariaJan 20 2023Reviewed by Aimee Molineux In a recent study published in JAMA Network Open, researchers identified factors related to PCC [post-COVID-19 study data implemented by the United States MHS . Adult MHS beneficiaries testing SARS-CoV-2-positive between 28 February 2020 and 31 December 2021 were included and followed up for one year.
For the present study, the date of the onset of symptoms or the first SARS-CoV-2-positive result was dated before 31 December 2021. COVID-19 status was based on reports of PCR analysis, documented in the healthcare records, self-reported throat or nasal swab test results indicating COVID-19, as mentioned in the survey, or specimens obtained during the study. The team excluded 549 individuals with suspected re-infections .
Results A total of 1,832 individuals were analyzed, of which 1,226 were aged between 18 and 44. The mean participant age was 41 years, 61% were men, 77% were non-vaccinated during the acute infection period, and 71% had no comorbid conditions. COVID-19-associated hospitalizations were documented for 13% of individuals. Among the participants, 40% had an illness lasting for ≥28.0 days [28 days to 89 days of illness duration among 364 individuals and ≥90.
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Wastewater-based monitoring of SARS-CoV-2 at UK airports and its potential role in international public health surveillanceIt is well established that air travel plays a key role in the global spread of many enteric and respiratory diseases, including COVID-19. Even with travel restrictions (e.g. mask wearing, negative COVID-19 test prior to departure), SARS-CoV-2 may be transmitted by asymptomatic or pre-symptomatic individuals carrying the virus. Due to the limitation of current clinical surveillance approaches, complementary methods need to be developed to allow estimation of the frequency of SARS-CoV-2 entry across international borders. Wastewater-based epidemiology (WBE) represents one such approach, allowing the unbiased sampling of SARS-CoV-2 carriage by passenger cohorts entering via airports. In this study, we monitored sewage in samples from terminals (n=150) and aircraft (n=32) at three major international airports in the UK for 1–3 weeks in March 2022. As the raw samples were more turbid than typical municipal wastewater, we used beef extract treatment followed by polyethylene glycol (PEG) precipitation to concentrate viruses, followed by reverse transcription quantitative PCR (RT-qPCR) for the detection of SARS-CoV-2 and a faecal indicator virus, crAssphage. All samples taken from sewers at the arrival terminals of Heathrow and Bristol airports, and 85% of samples taken from sites at Edinburgh airport, were positive for SARS-CoV-2. This suggests a high COVID-19 prevalence among passengers and/or airport staff members. Samples derived from aircraft also showed 93% SARS-CoV-2 positivity. No difference in viral prevalence was found before and after COVID-19 travel restrictions were lifted. Our results suggest that WBE is a useful tool for monitoring the global transfer rate of human pathogens and other disease-causing agents across international borders and should form part of wider international efforts to monitor and contain the spread of future disease outbreaks. BangorUni PLOSGPH many years ago, viruses traveled in birds, today they travel in first class.
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T-cell immunity and antibody responses against SARS-CoV-2 among individuals registered in the Bangkok home health care serviceT-cell immunity and antibody responses against SARS-CoV-2 among individuals registered in the Bangkok home health care service SciReports mahidolpr immunity SARSCoV2 COVID19 coronavirus covid health healthcare
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