Impact of antivenom administration on the evolution of cutaneous lesions in loxoscelism: A prospective observational study

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Study proves that antivenom reduces risk of skin necrosis in patients bitten by brown recluse spider

, which is a 2 immunoglobulin produced by the Instituto Butantan. It is dispensed in 5-ml vials, each milliliter capable of neutralizing 15 minimum necrotizing doses ofvenom. Patients in whom SAA administration was indicated first received an antihistamine and a corticosteroid . According to the Brazilian national guideline [

Laboratory tests were performed at admission, at the first week after discharge, and whenever considered necessary thereafter []. For patients diagnosed with cutaneous loxoscelism, prednisone was prescribed at discharge, as were an analgesic and an antihistamine for those who had pain and those who had pruritus, respectively.

 

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