By Dr. Sanchari Sinha Dutta, Ph.D.Jan 10 2023Reviewed by Aimee Molineux In an article published in the journal Nutrients, scientists have described the effectiveness of a specific diet containing fruit, avocado, whole grains, and trout in controlling inflammation and oxidative stress in obese individuals.
Strict adherence to a healthy lifestyle, including a healthy diet and daily physical activity, is the key to managing body weight. The Mediterranean diet and the Nordic diet are examples of healthy diets that are known to reduce obesity-related inflammation and oxidative stress. The experimental diet was composed of predominant foods of the Colombian coffee-growing zone, including fruits, avocados, whole grains, and trout. The control diet was composed of food items usually consumed by participants daily, including high-saturated fat foods, processed carbohydrates, and low-fiber foods.
Inflammation- and oxidative stress-related gene expression The real-time polymerase chain reaction based assessment of postprandial gene expression revealed that the experimental diet significantly reduces the expression of three inflammation-related genes, including nuclear factor kappa B subunit 1 , interleukin 6 , and IL1β.
A significant positive correlation was observed between the NFKB1 expression and blood triglyceride level 4 hours post-meal among individuals following the experimental diet. Among participants in the control diet group, a significant positive correlation was observed between the IL1β expression and blood insulin level 4 hours post-meal.