Germline variants associated with toxicity to immune checkpoint blockade - Nature Medicine

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A genome-wide association study in large cohorts of patients with different types of cancer treated with immune checkpoint inhibitors identifies genetic variants associated with immune-related adverse events immunotherapy GrohaStefanDrChoueiri

We thank all the patients who consented to participate in this study and the institutional data collection efforts that made this study possible. We thank M. Hassett, N. Lindeman, D. Liu, P. Lukasse, L. MacConnaill, P. Polak, S. Rodig, N. Zaitlen and E.

Stefan Groha, Sachet A. Shukla, Tanya E. Keenan, Eliezer Van Allen, Alexandra-Chloe Villani, Matthew L. Freedman & Alexander GusevStefan Groha, Guihong Wan, Alexandra-Chloe Villani, Kerry Reynolds, Yevgeniy Semenov, Toni K. Choueiri & Alexander GusevSarah Abou Alaiwi, Amin H. Nassar, Talal El Zarif, Elio Adib, Pier V. Nuzzo, David A. Braun & Toni K. Choueiri

Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA Wenxin Xu, Vivek Naranbhai, Ziad Bakouny, Talal El Zarif, Renee Maria Saliby, Andrew L. Schmidt, Chris Labaki, Sachet A. Shukla, Tanya E. Keenan, Eliezer Van Allen, Michael Manos, Osama Rahma, Matthew L. Freedman & Toni K. ChoueiriSarah Abou Alaiwi, Amin H. Nassar, Ziad Bakouny, Elio Adib, Osama Rahma & Toni K. ChoueiriGuihong Wan, Ahmad Rajeh & Yevgeniy Semenov

Department of Internal Medicine and Medical Specialties, School of Medicine, University of Genoa, Genoa, ItalyLowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USACenter of Molecular and Cellular Oncology, Yale Cancer Center, Yale School of Medicine, New Haven, CT, USASachet A. ShuklaTanya E.

 

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