that were missed on earlier imaging scans represent a"huge window of lost opportunity," say United Kingdom researchers who report a novel analysis.
The team studied 600 pancreatic cancer cases, including 46 cases categorized as post-imaging pancreatic cancer — cases not detected on imaging performed 3-18 months prior to diagnosis.The detailed analysis showed that 36% of cases of PIPC were potentially avoidable, reported first author Nosheen Umar, MD, a gastroenterology research fellow at the University of Birmingham, Birmingham, UK.
The findings are notable as the time window for curative PC surgery is often short, and missing the diagnosis on cross-sectional imaging can result in worse clinical outcomes for patients already dealing with a challenging cancer that has generally poor outcomes, Umar toldIn fact, pancreatic cancer has the lowest survival rate of all cancers in Europe, the UEG noted in a press release. Life expectancy at the time of diagnosis is just 4.6 months, and 5-year survival is less than 10%, Umar said.
Cases analyzed for the study were identified from electronic medical records of adults diagnosed with PC between 2016 and 2021 at two National Health Service providers. An algorithm was developed to categorize PIPC and assess potential causes of the missed diagnoses.
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