The state's seven-day average positivity was listed at 7.13% Thursday, compared to 7.61% last week. positivity was at 8.05%, down slightly from 8.09% last week.Across New England, states have seen a decrease in risk level in recent weeks as the summer surge continues to subside.remains in the medium risk category, while the southwest part of the state is now considered low risk. Aroostook, Hancock, Penobscot, Piscataquis and Washington are the medium risk counties.
Residents in areas with medium risk are encouraged to wear a mask if they have symptoms, a positive test or exposure to someone with COVID-19. Anyone at high risk for severe illness should also consider wearing a mask indoors in public and
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Frontiers | T cell perturbations persist for at least 6 months following hospitalization for COVID-19COVID-19 is being extensively studied, and much remains unknown regarding the long-term consequences of the disease on immune cells. The different arms of the immune system are interlinked, with humoral responses and the production of high-affinity antibodies being largely dependent on T cell immunity. Here, we longitudinally explored the effect COVID-19 has on T cell populations and the virus-specific T cells, as well as neutralizing antibody responses, for 6-7 months following hospitalization. The CD8+ TEMRA and exhausted CD57+CD8+ T cells were markedly affected with elevated levels that lasted long into convalescence. Further, markers associated with T-cell activation were upregulated at the inclusion, and in the case of CD69+CD4+ T cells this lasted all through the study duration. The levels of T cells expressing negative immune checkpoint molecules were increased in COVID-19 patients and sustained for a prolonged duration following recovery. Within 2-3 weeks after symptom onset, all COVID-19 patients developed anti-nucleocapsid IgG and spike-neutralizing IgG as well as SARS-CoV-2-specific T cell responses. In addition, we found alterations in follicular T helper (TFH) cell populations, such as enhanced TFH-TH2 following recovery from COVID-19. Our study revealed significant and long-term alterations in T cell populations and key events associated with COVID-19 pathogenesis.
Source: medical_xpress - 🏆 101. / 51 Read more »
Supplementary folic acid associated with higher risk of COVID-19 diagnosis and mortalityIn a recent study published in the journal BMJ Open, researchers investigated the impact of folic acid supplements and methotrexate, in combination or individually, on disease severity and mortality in coronavirus disease 2019 (COVID-19) cases.
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