L. flaviverrucosa
might make a few small, circular molecules called piperazyl molecules, which have been known to serve as useful scaffolds for synthesizing drugs.actually produces two types of piperazyl molecules. But these newfound compounds were different, produced by a single set of genes called a supercluster.
Once the researchers resolved the molecular structures of the two peculiar compounds, they also soon realized that one of them was quite unlike any described before. It consisted of two hexagonal molecules joined together to form a lopsided, asymmetric duo, which had potential drug-like activity when tested against certain types of human cancer cell lines.Blodgett.
Of course, we mustn't forget that testing drugs on lab-grown cell lines is a world away from treatments showing therapeutic benefit in clinical trials. Plus, it takes decades for potential drug candidates to make their way from the lab through testing and into the clinic, and many fail in the process.
"Much more work, focus and funding are needed for the novel approaches to result in effective antibacterial therapies to sustainably combat antibacterial resistance,"Still, the hope is that with more analyses like this one, which seek to identify which bacterial strains hold the most promise and which compounds are most likely to succeed, researchers are on the right track, with no time to lose.