‘An amazing ride’: Study offers dengue treatment hope | Malay Mail

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TOKYO, Oct 6 — Dengue affects tens of millions each year, producing the brutal symptoms that earned it the moniker “breakbone fever,” but new research may have found the first-ever treatment for the virus. Tests in cell cultures and mice found that a newly identified compound can effectively...

TOKYO, Oct 6 — Dengue affects tens of millions each year, producing the brutal symptoms that earned it the moniker “breakbone fever,” but new research may have found the first-ever treatment for the virus.

There is no doubt about the threat posed by the mosquito-borne dengue virus, which is estimated to infect at least 98 million people a year and is endemic in 128 countries worldwide. A vaccine called Dengvaxia is approved for use only in some countries and is effective against a single strain.Enter the unassumingly named JNJ-A07, a compound found by screening thousands of potential candidates, in a process researcher Johan Neyts described as like “looking for a needle in a haystack.”Its effect “in infected animals is unprecedented,” Neyts, who helped lead the research, told AFP.

Dengue can evolve quickly, and so the team also examined how JNJ-A07 would fare as the virus mutates.

 

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