Even the FDA's guidance for the authorization acknowledged that more clinical trials are needed to determine whether convalescent plasma is effective, and it went on to say that the treatment shouldn't be considered a new standard of care for the disease.
Among a subset of patients, those who received plasma with a higher level of COVID-19 antibodies were about a third less likely to have died within seven days, compared with those who received plasma with a lower level.Still, Dr. Michael Joyner of the Mayo Clinic, who is leading the nation's expanded access program, which has allowed more than 70,000 COVID-19 patients to receive convalescent plasma, said the findings"certainly meet the threshold" for an emergency use authorization.
There's science websites suggesting extracting plasma from sick person and resupplying it diluted and reconstituted might have benefit even without antibodies. Sounds like early stages of knowing possible benefits.
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