CRISPR used to treat cancer patients in first-of-its-kind U.S. study

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Doctors are genetically modifying the blood cells of patients with advanced cancer as part of the first U.S. study to use the gene-edited tool CRISPR to treat the disease.

Early results released on Wednesday show that immune system cells were successfully taken from the blood of three patients and genetically altered to help them recognize and fight cancer cells, and that the procedure appears to be safe.

All three patients had previously gone through other treatments without apparent success -- one patient's cancer continued to worsen, another showed no change, and a third was treated too recently for any potential progress to be reported. "Our plan is to treat more patients and we've demonstrated that we've done it safely and that the cells have worked," says Stadtmauer. "In terms of responses, we still have a-ways to go to see whether these patients are benefiting from this treatment."

While it is too early to determine whether the treatment will actually treat the cancer, the point of the study is to make sure the procedure is safe and feasible. Once given FDA approval, doctors say they will be able to target different genes to attack the cancer more effectively.

 

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It's amazing what they can do now!

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