Doctors use CRISPR gene editing in cancer patients, a first in the U.S.

After two to three months, one patient’s cancer continued to worsen and another patient was stable. The third patient was treated too recently to know how she’ll fare. The plan is to treat 15 more patients and assess safety and how well it works., a cancer specialist at the Cleveland Clinic who is not involved in the trial.

Other cell therapies for some blood cancers “have been a huge hit, taking diseases that are uncurable and curing them,” and the gene editing may give a way to improve on those, Gerds said. Gene editing is a way to permanently change DNA to attack the root causes of a disease. CRISPR is a tool to cut DNA at a specific spot. It’s long been used in the lab and is being tried for other diseases.

It wasn't used in patients, it was used in a petri dish.

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