—and the dry, itchy, scaly patches of skin that it causes—doesn’t usually go down without a fight. And, if your symptoms haven’t responded to topical treatments or you have certain types of psoriasis that can be challenging to treat, youras a treatment for your psoriasis. To which you might say, understandably, “What the heck is a biologic?”
Biologics that target TNF-alpha are generally older drugs and, because TNF-alpha is involved in a lot of normal bodily processes outside of psoriasis, targeting it could come with more side effects than newer options. Specifically, TNF-alpha is a type of protein called a cytokine, and it has actions all over the body related to infections and inflammation.
Depending on your exact symptoms, your doctor may recommend combining your biologic with another treatment, like topical medications or UV therapy. But biologics aren’t usually combined with each other, Dr. Cheng says.
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