. Another similar study — also published in the But both trials found differences in how well the ring worked for women based on age — mostly because women younger than 21 , researchers hypothesised, and they were likely having more sex than older women.
After the initial study concluded in Uganda and South Africa, scientists continued to follow ring-using women who had remained HIV negative during the trial for at least one year. They found that not only did 95% — 12% more than in the previous study — of women use the ring at least some if not all of the time, but also that the silicon band was more effective at protecting them from HIV than . The research was presented at the South African Aids Conference in May.
IPM’s chief medical officer Annalene Nel says the organisation plans to submit the ring for approval to the South African Health Products Regulatory Authority and its United States counterpart, the Food and Drug Administration, later this year. The band is already being reviewed by the European Union’s drug authority, the European Medicines Agency. If the agency greenlights the ring’s public use in the EU, IPM will submit it for World Health Organisation prequalification. This kind of WHO approval often allows devices to be used in low- and middle-income countries that don’t have national regulators with the capacity to quickly approve new medicines or products.
The IPM expects the ring to be WHO-prequalified by mid-2020 and approvals from several national regulators in Africa to follow, says the senior director of IPM external affairs Africa, Leonard Solai.that could be left in for three months at a time or could combine the HIV protection of an ARV with a long-acting contraceptive. A two-in-one ring could cut down costs for women, for instance, the money spent on transport to collect birth-control from clinics that are at times few and far between.
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