In fighting cancer, look to what other animals do

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Elephants have a cancer-mortality rate of about 5%, compared to 11-25% in humans

because people have them too. But whales may also harbour tumour-fighting genes unknown to science. The next step is therefore to irradiate laboratory-grown lines of whale cells, in order to encourage cancer-causing mutations and thus find out which genes become active in an attempt to clamp down on those mutations. The eventual goal is to discover which strategies whale genes use to combat cancer.

Similar studies are already being done using cancer-fighting proteins from another group of giants—elephants. These have a cancer-mortality rate of about 5%, compared with 11-25% in human populations. Some participants in the whale study were previously involved in sequencing African and Asian elephant genomes. They found that an important weapon in the elephants’ arsenal is, a gene that encodes an apoptosis-inducing protein called p53.

Dr Tollis, Dr Maley and their colleagues will also search for tumour-suppressing genes in previously sequenced genomes available in public databases. These include about 65 species of mammal—some of which, such as naked mole rats, are noted for low cancer rates even though they are small compared with elephants and whales, and so do not seem to conform to Peto’s paradox. The search will also look at non-mammalian exceptions to the paradox, such as crocodiles and birds.

One novel aspect of all this research is its willingness to take the animals under study on their own terms. Medical science uses animals a lot—but almost always they are there to act as stand-ins for human beings, a role encapsulated in the word “model” that is often applied to such laboratory organisms. Comparative oncology explicitly rejects this idea.

 

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A pay wall to read this , really ? Pffff. Unfollowed.

That would be great news for people who are suffering

Because big ones have slower metabolism(and cancer is correlated with metabolism rate. . Nothing applicable to humans from this study; it is an existing correlation.

Look to the birds of the air & the fish of the sea...

new play ground for bio-simulating technoligy

alllibertynews Yeah but we have 100+ genders so elephants can suck it!

What kind of elephant is that?

That’s a whale not an elephant.

I’m sure science is in on this! Would be ground breaking.

How many genders do they have?

Would have thought that since 'Elephants never forget,' they have 20X the number of Alzheimer's-fighting genes as compared to humans.. - Elephants have 40 versions of a cancer-fighting gene, whereas humans have only two

I take it that’s a picture of an elephant post the aquatic pivot. Sea creatures just scale better

That’s a whale

That’s a very strange looking elephant 🐘!

Life finds a way

Guys..I’m not a zoologist but I’m 80% sure that’s not an elephant

This’s the gift of nature! Better to extract that elephants’ hormone and implant to humans.

Diseases are man - made everything we eat put carcinogens

Good thing nature isn’t copyrighted

maybe we should take that as a hint - Mother Nature doesn't like us, and rightfully so

Well now looks like we are onto something here oncology building for better outcomes HealthScience HealthEconomist DCarsonCPAonHealth Thingsthatmakeyougohmmm built at the cross roads of FinancialValue and HumanValue for the ValueinContext to Entity, Policy and Community

Elephants also have genes that make them look like a whale 40 times in their life span.

Poor elephants. Survive cancer just to be killed by millionaires who love safaris and blood .

... didn’t know elephants had fins...

Maybe the solution to the cancer vaccine problem is elephants🤔

so elephants is bettet than human in genes?

Don't harm to elephants Don't experiment with elephants

that elephant can swim!

Elephants are cited in your lede in, but you image a whale. Um, ok.

csiswim so let's CRISPR that shit and move on...oh wait. maybe, just maybe, this is how biology works on its own...

jplau1 Proving that Elephants have evolved much better than humans have.

In Vietnamese language, that animal was named elephant fish. Any missing word ?

Not a photo of an elephant.

amazing

Let’s eat their diets.... peanuts.

VaGyver Plus, elephants don’t smoke

elephants or whale?

And elephants don't even smoke

Are they doing something to avoid cancer?

But elephants, unfortunately, also have us

That is not an Elephant 😁

Who has only two cancer fighting genes and refuses to change their cancer causing lifestyle despite the changes not being that difficult?

Haven't read yet, but my instincts say it is because they are a much older species than homo sapiens.

It makes sense that huge bodies would be more vulnerable to overgrowth, just from their sheer volume of cells. Consequently bigger bodies would need more active countermeasures to combat overgrowth.

Ah yes the famous Sea Elephant and their infamous resistance to cancer

They are gonna need those 40 versions with the way we treat the oceans.

Can we borrow theirs

Elephants also look like whales. 🤷🏽‍♀️

yeah and the Trumps keep shooting them like they're fucking fair games

It's Natural Creation,,,what we needed and what he needed...

Ganpati bapa morya

Shape of water was predicting the future!

got those genes that make em look like whales too

oh damn. We should be whales.

because humans aren t kind

is the reason why Japanese eat elephant?

🤔🤔🤔now I know why they are so big😂😂😂

Yet Elephants are peaceful in waters.

They have trunks and tusks as well.

I may be a fool to ask this ....why 'Heart Cancer ' is not heard of?

Humans may have 40 times more sense to lead a healthier way of life to *minimize* the chance of getting cancer.

um that’s a whale

Am I an elephant? Or a human? [In this context] Asks this Ganesha.

We could add 40 genes to our DNA with genetic engineering.

Hence, a picture of a whale.

They have one extra version to acquire in order to outlive humans, the gene to fight human predatory behavior against them.

There you go. Free from next time go there for your images 😂😂

Is whale’s picture cheaper? Economist

Sounds like we need to evolve faster

What wisdom can whales impart to us on this front awhalefact?

this is a whale.

it doesn't pay to be big unless you're long-lived. And you can't be long-lived unless you've fought cancer to a stand-still. So yeah, any large animal we encounter knows something.

LETS KILL & STUDY THE ELEPHANTS TO BE IMMORTAL‼️👀

So eating elephants can...be helpful in...cancer?🤔

yashar

I’m pretty sure this is one of those sea elephants...

Oceanic fauna and flora has a key to a good hello in our life. How the world responds to the good gestures from the Oceans will certainly make curiosity great for the continuation of good life.

Peto’s Paradox

LASR2nd Beautiful 😍

I’m a fat fuck, so I’m hoping that’s me sorted.

May be they are a 'liitle' clever than us ? What a wonderful world where people with big money are free todo whatever they want !!!

1 Trillion Dollars for an ET craft. DISCUSS.

Maybe not eating horribly processed foods and eating/breathing/being surrounded by chemicals may be a place to start ...🤔

That's one interesting looking elephant ! Lol

Not an elephant. Part of trump's intelligence test. He dint answer.

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