Gut feelings: How microbes may affect your mental health

I suffer from depression and I’ve been reading lately that microbes in the gut can affect your mental health. If I take a probiotic supplement that changes my gut microbes, will that make me feel better?The medical community has long known that the trillions of microbes that inhabit the human gut perform many essential jobs.

Collins says that the bacteria used in his study somehow modified the body’s immune system, which in turn triggered a positive response in brain cells. It’s also possible that gut microbes may produce compounds that directly or indirectly affect the brain. But figuring out exactly what’s going on isn’t easy because depression itself is a complicated condition.

Both Collins and Sinyor think it’s possible that research may eventually lead to new bacterial-based treatments for depression and other mental-health disorders. But such therapies may help only some patients. That means it may be extremely difficult to alter an individual’s gut bacteria in a sustainable way. Despite these obstacles, some companies are already vigorously marketing their supplements, which contain an assortment of bacterial strains, as remedies for mental-health problems.

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