REUTERS: Array BioPharma Inc's cocktail of three therapies helped patients with a type of colorectal cancer live longer than those on standard treatment, according to interim results of a late-stage study on Tuesday.
Array's combination also helped reduce the risk of death from colorectal cancer by 48per cent compared to the standard of care in patients, with a gene mutation known as BRAF V600E, whose cancer had progressed after one or two other therapies. Colorectal cancer is the third leading cause of cancer-related deaths in men and women, and about 145,600 new cases of colon or rectal cancer are expected in the United States in 2019, according to the American Cancer Society.The company said it is testing the combination as a potential first-line treatment for colorectal cancer patients with the BRAF V600E mutation in a separate study.
In the latest study, Array also tested a double-combination version of the therapy, which helped reduce the risk of death by 40per cent, with a median overall survival rate of 8.4 months.
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