Research reveals optimal magnesium levels could lower dementia risk

By Dr. Chinta SidharthanReviewed by Susha Cheriyedath, M.Sc.Jul 15 2024 In a recent study published in the journal Advances in Nutrition, scientists in the United States conducted a systematic review of randomized controlled trials and cohort-based studies to examine whether various measures of magnesium levels, such as biomarkers, dietary intake, or supplements, were associated with cognitive health and neurological functioning in adults.

Modifiable risk factors for dementia, such as stress, depression, vascular health, and lifestyle factors, must be targeted to effectively lower the incidence or slow the progression of dementia and reduce the economic and social burden exerted by the disease. Electrolytes have been found to play an important role in neurological health. Magnesium plays a vital role in cellular function and neuronal health, and its deficiency has been linked to memory impairments and Alzheimer’s disease.

Studies on animal models have also shown that magnesium deficiency is linked to memory impairments associated with hippocampal activity, and oral administration of magnesium has been found to lower neuroinflammation. Dose-curve responses were created after the cohort studies were analyzed for the type of exposure. Furthermore, the researchers used three models to evaluate the association between magnesium exposures and cognitive outcomes.

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