By Pooja Toshniwal PahariaReviewed by Danielle Ellis, B.Sc.Jul 4 2024 In a recent study published in JAMA Surgery, researchers investigated whether Roux-en-Y gastric bypass reduces cardiovascular risk factors independent of calorie restriction and weight loss.
About the study In the present non-randomized controlled trial, researchers evaluated the changes in cardiovascular risk variables over six weeks in obese individuals who underwent either a very low-energy diet or Roux-en-Y gastric bypass surgery along with corresponding caloric restrictions and weight reduction.
The researchers conducted assessments at week 0 , week 3 , week 5, and week 9 to assess changes in protein/peptide, metabolite, and bile acid in patients undergoing RYGB vs. VLED with matching weight loss. Evaluation parameters included C-peptide, heart rate, low-density lipoprotein , high-density lipoprotein , apolipoprotein B, triglycerides, lipoprotein , total cholesterol, fat-free mass, and fat mass.
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