New HIV test targets neglected strains in global cure hunt

Weill Cornell MedicineJul 3 2024

Dr. Guinevere Lee, Assistant Professor, Virology in Medicine, Division of Infectious Diseases, Weill Cornell MedicineThe findings show-;like other studies in developed countries-;that HIV strains circulating in Africa establish viral reservoirs in the human body. Although antiretroviral therapy can reduce the level of HIV in the blood to an undetectable level, these dormant reservoirs continue to survive.

Related StoriesThe team then modified existing laboratory tests that identify HIV subtype B proviruses to detect proviruses that are subtypes A1 and D. "The new assay we've developed will help researchers home in on the intact proviral genomes relevant to HIV cure research for patients affected by these under studied strains," Dr. Lee said.

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