By Dr. Priyom Bose, Ph.D.Reviewed by Benedette Cuffari, M.Sc.Jul 2 2024 A recent Nutrients journal study assesses the possible interplay between inflammation, carbohydrate intake, and the development of atherosclerotic cardiovascular disease development.
Although the role of carbohydrates in insulin secretion and fat storage is well-documented, a direct link to inflammatory effects has not been established. Some studies have reported that a low-carbohydrate diet is associated with greater reductions in inflammatory marker levels compared to low-fat diets.
Related StoriesA total of 3,042 individuals from Attica, Greece, were invited to participate in the study. Balanced representation was ensured by stratifying participants based on specific characteristics like age, sex, and region, following the demographics of the 2001 census. At baseline, the study participants did not have preexisting CVD, chronic inflammatory conditions, or cancer.
Carbohydrate intake alone was not associated with an increased risk of developing CVDs. However, considering both carbohydrate quantity and quality, along with inflammatory marker levels, was found to affect the risk of CVD. This association persisted when CVD risk factors, including sex, obesity, hypertension, hypercholesterolemia, diabetes, smoking, physical inactivity, and low adherence to the Mediterranean diet, were considered.
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