Is Anxiety a Prodromal Feature of Parkinson's Disease?

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Parkinson's Disease News

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People with anxiety were twice as likely to develop Parkinson's as those without anxiety. Investigators say the findings suggest anxiety may be a prodromal feature of PD.

Individuals with anxiety have at least a twofold higher risk of developing Parkinson's disease than those without anxiety, new research suggested.

"Anxiety is known to be a feature of the early stages of Parkinson's disease, but prior to our study, the prospective risk of Parkinson's in those over the age of 50 with new-onset anxiety was unknown," colead author Juan Bazo Alvarez, a senior research fellow in the Division of Epidemiology and Health at University College London, London, England, said in a news release.

Features of PD such as sleep problems, depression, tremor, and impaired balance were then tracked from the point of the anxiety diagnosis until 1 year before the PD diagnosis. After adjustment for age, sex, social deprivation, lifestyle factors, severe mental illness, head trauma, and dementia, the risk for PD was double in those with anxiety compared with the non-anxiety group .The researchers identified specific symptoms that were associated with later development of PD in those with anxiety, including depression, sleep disturbance, fatigue, and cognitive impairment, among other symptoms.

 

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