The European Medicines Agency has recommended the first emergency treatment for allergic reactions to be administered as a nasal spray, not as an injection.and idiopathic or exercise induced anaphylaxis, the agency's Committee for Medicinal Products for Human Use decided at its June meeting.
Treatment with epinephrine, also known as adrenaline, decreases the anaphylactic reaction by binding to adrenergic receptors, inhibiting the widening of blood vessels and blood vessel permeability induced by histamine during anaphylaxis. Adrenaline also relaxes the smooth muscles in the lungs. This leads to improved blood flow and easier breathing.