Barcelona Institute for Global Health Jun 27 2024 A study led by the Barcelona Institute for Global Health , a centre supported by the "la Caixa" Foundation, provides new evidence on the adverse effects of prenatal exposure to ethylene oxide on fetal development. The results, published in Epidemiology, show that increased EO exposure in utero is associated with a reduction in birth weight and head circumference in newborns.
This new study focused on pregnant women and newborns in the general population, rather than a specific population with known high levels of EO exposure. The research team looked at the levels of EO hemoglobin adducts in the cord blood of 1,106 newborns from 5 countries: Greece, Spain, Norway, UK and Denmark.
Higher exposure, lower birth weight and smaller head circumference The results of the study showed that median levels of EO-Hb adducts in the umbilical cord were higher in smoking mothers compared to non-smoking mothers. Higher levels of hemoglobin adducts were associated with lower birth weight. Specifically, mean birth weight decreased by 3.30 grams with each 10 pmol/g increase in hemoglobin adducts.
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