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Treatment for autoimmune disorder acts on balance of immune cell types

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Immune System News

Lymphoma,Medical Topics,Lupus

Autoimmune diseases cannot currently be cured, only treated, and this is also true for neuromyelitis optica spectrum disorder, which affects the central nervous system. A study of how the treatment acts on the immune system shows that it shifts the balance of types of immune cells.

This finding may represent a step toward the development of personalized medicine for autoimmune diseases.

The Kobe University neurologist CHIHARA Norio specializes on the disease and recently wondered:"B cells are a type of key immune cells that respond to inflammatory signals, and in autoimmune diseases like NMOSD, they produce antibodies against part of the body itself, exacerbating the condition. Therapies that inhibit inflammatory signals were therefore expected to change the activity of B cells in NMOSD.

This research was funded by the Japan Society for the Promotion of Science , the Japan Agency for Medical Research and Development , the Japan Science and Technology Agency , and the Ministry of Education, Culture, Sports, Science and Technology Japan . It was conducted in collaboration with researchers from The University of Tokyo.

 

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