Engineering Mind Helps Investigator Develop Cancer Therapies

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Colorectal Cancer News

Colorectal Cancer (CRC),Cancer,Malignant Neoplasia

A prominent colorectal cancer researcher was recently recognized for his role in setting new standards of care for BRAF-mutated metastatic colorectal cancer.

in April. The American Association for Cancer Research granted Dr Kopetz this award to recognize his leadership in the development of novel therapies for patients withUsing molecular profiling and patient-derived xenografts, Dr Kopetz discovered resistance mechanisms and helped develop approaches to overcome such resistant pathways.

One day a week, I was at Georgetown in the HIV/AIDS Clinic, where I collected blood samples and saw HIV/AIDS patients. At the end of the summer, I reflected and realized that I really enjoyed that 1 day out of the week, much more than the other 4. I enjoyed working with patients and interacting with people and thought I'd enjoy the more direct way to help patients, so made a pivot into medicine.My path was a little atypical for a physician scientist.

Our ability to extract information out of patient biopsies, surgical samples, or even minimally invasive techniques to sample the tumors, such as liquid biopsy, has provided tremendous insights into how tumors are evolving and adapting to therapies and opportunities for novel interventions. This opens up ways where I think as a field, we can more readily accelerate our understanding of cancer.

Today, I do a lot of work understanding and recognizing complex networks of signaling, and it's the same network theories that we learned and developed in engineering.

 

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