Your Good Health: Biphosphonates can worsen esophageal disorders

Dear Dr. Roach: I’m a 68-year-old female with osteopenia. My doctor wants me to take a bone medication such as Boniva or Fosamax. I’ve read that folks with esophageal issues may be harmed by taking these. Can you explain why?First off, we don’t usually treat isolated low bone mass with powerful medicines like the ones you mention, which are both bisphosphonates. .

The issue with the esophagus is that if pills get stuck in the esophagus, they can cause severe damage to it. So, people with esophageal disorders — such as achalasia, esophageal stricture or varices, or Barrett’s esophagus — should not take these types of medicines by mouth. People with reflux without these complications can take oral bisphosphonates as long as they can comply with staying upright for 30 minutes after taking them.

The most common HPV-related cancer in men is head and neck cancer. HPV is now the leading cause of head and neck cancer. Most of these cases in men occur from sexually acquired HPV infection. Men are at a higher risk for HPV-related head and neck cancer than women, even though women are at a much higher risk for the overall HPV-related cancers, since cervical cancer unfortunately remains common.

By far, the best way to prevent HPV transmission is vaccination. The HPV vaccine is highly effective at preventing infection if it is given before the onset of sexual activity, but it may still be fully or partially effective after the onset of sexual infection.

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