Study Confirms Sweeteners Do Not Spike Hunger Levels and Identifies Additional Health Benefits

A comprehensive study led by the University of Leeds found that replacing sugar with sweeteners in foods does not increase hunger and helps lower blood sugar levels, beneficial for people at risk of type 2 diabetes. The study, part of a European consortium, confirmed that using sweeteners can reduce sugar intake without negatively affecting appetite or causing undesirable health effects, providing a valuable tool for managing diet and preventing obesity-related conditions.

The double-blind randomized controlled trial found that consuming food containing sweeteners produced a similar reduction in appetite sensations and appetite-related hormone responses as sugary foods – and provides some benefits such as lowering blood sugar, which may be particularly important in people at risk of developing type 2 diabetes.

The trial was led by the University of Leeds in collaboration with the The Rhône-Alpes Research Center for Human Nutrition. It is the latest study to be published by theof 29 European research, consumer, and industry partners which is working to develop and review evidence on long term benefits and potential risks involved in switching over to sweeteners and sweetness enhancers in the context of public health and safety, obesity, and sustainability. It was funded by Horizon Europe.

“Our study provides crucial evidence supporting the day-to-day use of sweeteners and sweetness enhancers for body weight and blood sugar control.”The study, which is the first of its kind, looked at the effects of consuming biscuits containing either sugar or two types of food sweetener: natural sugar substitute Stevia, or artificial sweetener Neotame on 53 adult men and women with overweight or obesity.

The new trial took place at the University of Leeds and the Rhône-Alpes Research Center for Human Nutrition , France between 2021 and 2022. Participants were all aged 18 to 60, with overweight or obesity. After consuming the biscuits, they were asked to rate how full they felt over several hours. Glucose and insulin levels were measured, as were ghrelin, glucagon-like peptide 1, and pancreatic polypeptide – hormones associated with the consumption of food.

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