Kathy Schwartz was 10 years free from alcohol, cigarettes and opiates but every day it was painful to control her cravings. “They were always in the background,” she says. In June last year, however, this noise fell silent.
Prescribed the weight-loss drug semaglutide, she not only lost nearly 30 kilograms over 10 months, but also her desire to reach for a drink or take some pills. “I do not crave, which I didn’t think would be a side effect,” says Schwartz. Remarkably, theSchwartz isn’t alone in this experience.
It is early days, but there are hints that these drugs could be repurposed to treat depression, anxiety, addiction and even certain eating disorders – as well as neurological conditions such as Parkinson’s disease and Alzheimer’s. What’s more, it seems that these effects aren’t just mediated via weight loss, but through direct action on the brain. could stimulate insulin production when injected into rodents in the lab. More surprisingly, these animals started eating less and losing weight.
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