Brain cancer is difficult to treat when it starts growing, and a prevalent type, known as a glioma, has a poor five-year survival rate. In a new study published in, Mayo Clinic researchers report on a new surgical platform used during surgery that informs critical decision-making about tumor treatment within minutes. Time is of the utmost importance when dealing with aggressive malignant tumors.
Each tissue sample was placed on a glass slide steps away from the patients during ongoing surgery. The samples were analyzed through the mass spectrometer, which allowed researchers to rapidly assess -- within two minutes -- whether an IDH mutation was present. "The ability to identify this mutation during brain surgery means that we can treat patients locally before they leave the operating room," says the study's senior author, Alfredo Quiñones-Hinojosa, M.D., dean of research and chair of the Department of Neurosurgery at Mayo Clinic in Florida.
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