Heart healthy behaviors may slow biological aging, research shows

The benefit of better heart health may be associated with the positive impact of heart healthy lifestyle factors on biological aging , according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

Jiantao Ma, Ph.D., senior study author and assistant professor in the division of nutrition epidemiology and data science at the Friedman School of Nutrition Science and Policy at Tufts University, Boston Researchers examined health data for 5,682 adults who were enrolled in the Framingham Heart Study, an ongoing, large, multigenerational research project aimed at identifying risk factors for heart disease. Using interviews, physical exams and laboratory tests, all participants were assessed using the American Heart Association's Life's Essential 8 tool. The tool scores cardiovascular health between 0-100 using a composite of four behavioral measures and four clinical measurements .

"We know that modifiable risk factors and DNA methylation are independently associated with cardiovascular disease. What this study adds is that DNA methylation may serve as a mediator between risk factors and cardiovascular disease," said Foraker, who is a professor of medicine at the Institute for Informatics, Data Science and Biostatistics and director of the Center for Population Health Informatics, both at Washington University School of Medicine in St. Louis, Missouri.

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