A University of Saskatchewan research team's discovery of the additional health benefits of an appetite-suppressing protein has doubled the potential for scientists to find new avenues for treating obesity and metabolic disorders in animals and people.highlight their discovery of the lipid-lowering effects of nesfatin-1-like peptide . This newly identified peptide -- or small protein -- is a close relative of nesfatin-1 , which regulates feed intake and body weight.
"We are far away from bringing these findings to bedside," said Unniappan."But we now have additional multiple targets available that could be explored for lipid disease treatment and therapeutic advancements." Unniappan and his research team have been at the forefront of nesfatin-1 research. Discovered in 2006 by a group of researchers in Japan, nesfatin-1 was initially recognized for its ability to suppress food intake.
Discovering such results -- that administering NLP reduces lipid levels, while disrupting its production alters lipid metabolism -- reinforces its pivotal role in metabolic regulation. "It's beautiful to know the same peptide can achieve so many meritorious health effects, that in combination have the potential to help both human and animal patients," said Unniappan.
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